PHYTOSOMES: A NEW VESICULAR DELIVERY FOR HERBAL MEDICINEAbstract
Phytoconstituents like flavonoids, tannins, glycosides, alkaloids and terpenoids have medicinal values. In recent years herbal medicines are developed and used to treat almost all diseases with lesser or no side effects. But the plant constituents having low half-life, poor bioavailability and stability problems because of their high particle size and high aqueous solubility. Phytosomes are the carriers for the novel drug delivery system. It consists of two words “phyto” means “plant” and “some” means “cell-like”. They are used to improve the absorption, systemic bio-availability and prolongs their release by complexing with the phospholipids. It forms a weak hydrogen bond between polar heads while non-polar tail of phospholipids encloses over complex thereby imparts lipophilic character to herbal extracts. Hence increases the absorption of plant constituents than the conventional herbal extract. The current review describes the overview of phytosomes and its properties, method of preparations, evaluations of novel technologies and importance of phytosomes.
Varalakshmi Mummidi * and Pushpalatha Kondamuri
School of Pharmaceutical Sciences and Technologies, Jawaharlal Nehru Technological University Kakinada (JNTUK), East Godavari, Andhra Pradesh, India.
19 September 2020
30 April 2021
25 May 2021
10.13040/IJPSR.0975-8232.12 (11). 5634-41
01 November 2021