PHYTOTHERAPY IN FUNCTIONAL HEPATIC INJURYAbstract
Since ancient times, natural products, especially plants have been utilized to treat variety of disorders, and an astounding number of contemporary medications have been created from them. All across the world, liver problems are prevalent. These conditions are only mildly handled traditionally; however, allopathic treatment always makes the situation worse when used to address more severe conditions. The current review offers summaries of plants (44 species from various families) with hepatoprotective qualities that may be discovered in literature sources from various databases and are properly categorized based on the parts utilized. Through the use of experimental animal models, all the plants were examined scientifically for their ability to protect the liver by testing certain parameters, such as liver indicators (AST, ALT, ALP, total protein content, albumin, and bilirubin), as well as through histological analysis, the hepatoprotective action was scientifically demonstrated. From the review, phytoconstituents such flavonoids, glycosides, terpenoids, and alkaloids are primarily responsible for medicinal plants’ hepatoprotective properties. It will be useful for the researchers to discover a field of traditional systems of medicine. Professionals will find it useful to learn about the world of conventional medical practice. More research on these plants is necessary to evaluate their effectiveness, safety for use around sensitive organs, and precise mechanisms of action in the treatment of liver disorders.
Srikar Barik *, P. K. Panda and Diptimayee Jena
Department of Pharmacology, UDPS, Utkal University, Vanivihar, Bhubaneswar, Odisha, India.
10 March 2023
05 June 2023
28 June 2023
01 November 2023