PORTRAYAL EXPLORATION OF PHARMACEUTICAL NANOPARTICLESAbstract
Nanotechnology has found its way into most science fields at a tiny scale. Particle of this size and molecules were found to work differently and got diverse applications. Novel drug delivery system leads to the development of Nanocarriers, including Nanoparticles, Nanospheres, Nano capsules, Nano emulsion, liposomes, and Niosomes. The major area for research is to design Nanoparticles that can efficiently manage particle size, surface properties, and drug release. For this to get characterizations of Nanoparticles, it is critical to control their desired in-vitro and in-vivo behavior. Nanoparticles are characterized by their size, surface morphology, and surface charge, using highly advanced microscopic techniques. Colloidal stability is ascertained through zeta potential. Nanoparticles are also characterized by polymer and drug interaction. In-vivo characterization for binding and internalization of targeted carriers to the specific cell and bio distribution study of targeted Nanoparticles could also be confirmed using confocal microscopy. This review covers all the aspects related to the characterization of the pharmaceutical Nanoparticle.
D. S. Warekar *, N. Kurup and V. Kulkarni
Department of Pharmaceutics, Principal K. M. Kundnani College of Pharmacy, Jot Joy Building, Ram Bhau Sal Gaonkar Road, Cuffe Parade, Colaba, Mumbai, Maharashtra, India.
16 January 2023
27 April 2023
31 May 2023
01 October 2023