PREVALENCE OF HYPOTHYROIDISM AND ITS CO-MORBIDITIES IN RELATION TO THE CAUSES AND RISK FACTORS IN PATIENTS UNDERGOING LEVOTHYROXINE THERAPYAbstract
Hypothyroidism is a metabolic disorder, which results in slower rate of metabolism leading to life threatening medical conditions like diabetes and other complications. This study aims to analyze the prevalence of hypothyroidism and its co-morbidities in relation to the causes and risk factors in patients undergoing levothyroxine therapy and to know the adherence level of prescribers to the Thyroid Dysfunction and Dyslipidemia Guidelines of Indian Thyroid Society. Methods: This was a cross-sectional, observational, questionnaire-based, single visit study, which included adult patients who were on levothyroxine treatment for at least three months prior to enrolment. Demographic details, data pertaining to etiology of hypothyroidism, the dose of thyroxine used, comorbid conditions, and concomitant medications used were also documented. Compliance to Thyroid Dysfunction and Dyslipidemia Guidelines of Indian Thyroid Society was assessed and documented. Results 32% of the study population suffered from primary hypothyroidism. It was also found out that levothyroxine was given along with so many other medication classes with cardiovascular system drugs being the most prescribed medications. Regarding adherence to Thyroid Dysfunction and Dyslipidemia Guidelines of Indian Thyroid Society, only 18 patients out of 59 patients who have elevated lipid levels were subjected to tests for hypothyroidism Conclusion: This study warrants the inclusion of thyroid profiling as a compulsory evaluation parameter in all patients who are obese and in those who report elevated lipid profiles. Higher prevalence in female population in this study calls for larger studies focused on the female population. Thyroid Dysfunction and Dyslipidemia Guidelines of Indian Thyroid Society should be brought to practice if we are interested in preventive care
A. Anandhasayanam , T. Arivudainambi , S. Kannan and Sam Johnson Udaya Chander J.*
Department of Pharmacy Practice, RVS College of Pharmaceutical Sciences, Coimbatore, TN, India.
09 September, 2015
29 December, 2015
05 January, 2016
01 March, 2016