PREVALENCE OF SERUM THYROID HORMONES AND MENSTRUAL IRREGULARETIES WITH INFERTILITY IN UTTAR PRADESH, INDIAAbstract
It is important to predict the serum thyroid hormones level in females during infertility to prevent its occurrence later on. In this study, we studied serum thyroid hormones and menstrual irregularities during infertility. A case control study was performed in 75 infertile patients with menstrual irregularities and 50 healthy matched women. Three biochemical parameters were measured in serum, hormones triiodothyronine (T3), tetra-iodothyronine (T4) and serum thyroid stimulating hormone (TSH) by TOSOH-AIA-360, immunoassay method. Out of 75 infertile women sixteen percent (16%) had menstrual irregularities with hypothyroidism. The mean serum thyroid level in 75 infertile women were 0.88±0.34 ng/ml, 7.69±2.87 μIu/dl and 5.43±6.88 μIu/ml, respectively. Serum T3, T4 and TSH level were statistically highly significant in infertile women. Serum thyroid stimulating hormone level was found at higher side in infertile women. High incidence of hypothyroidism was found in infertile women and it shows a positive correlation with menstrual disorder.
Neha Sharma* and Simant Baliar Singh
Department of Biochemistry, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly- 243 202, Uttar Pradesh, India
08 May, 2012
22 August, 2012
29 August, 2012
01 September, 2012