PRONIOSOMES AND ETHOSOMES: NEW PROSPECT IN TRANSDERMAL AND DERMAL DRUG DELIVERY SYSTEMAbstract
The present article is a descriptive study of the performances of ethosomes and proniosomes as specialized delivery systems for transdermal drug delivery system. Vesicular systems, such as ethosomes and proniosomes are used in cosmetic and pharmaceutical products to encapsulate ingredients, to protect ingredients from degradation, to increase bioavailability, and to improve cosmetic performance. A review of literature is presented here and a sincere attempt has been made to highlight the properties and characteristics of proniosomes and ethosomes in transdermal drug delivery and cosmetic/cosmeceuticals applications. Interaction studies between proniosomes and ethosomes components and skin is also discussed along with the formulation aspects of proniosomes and ethosomes formulation. Our aim is to introduce and explore proniosome and ethosomes as a carrier system for various applications of drugs and cosmeceuticals. The goal of this study is to investigate the efficiency of transcellular delivery of drugs with the help of ethosomes and proniosomes.