PROSPECTIVE OBSERVATIONAL STUDY ON PERI-OPERATIVE USAGE PATTERN OF ANALGESICS
AbstractThe present work reports a prospective observational study to determine perioperative usage pattern of analgesics. Both general and regional anaesthesia and also different analgesics which is most effective to manage post operative pain were used. 120 patients were studied randomly as per criteria. Techniques of anaesthesia, pre, peri& post operative vitals and pain scores were noted in selected time interval. Pain score recorded 0-3 as mild, 4-6 as moderate & 7-10 as severe. Of all the analgesics administered in peri & postoperative period, Fentanyl (F) alone & in combination with diclofenac (D) were used maximum in perioperative period. These two groups were compared. In postoperative GA cases, majority patients received paracetamol (P) and tramadol (T) and in regional blocks, Pethidine (PE) Phenergan (PH) combination & tramadol were used. These groups werecompared to evaluate pain perception. Fentanyl alone found to be more effectivein maintaining hemodynamic stability. In fentanyl-diclofenac combination, pulse rate and blood pressure were higher than fentanyl alone. Pain scores were significantly higher in GA compared to regional blocks. In GA patients, fentanyl-paracetamol combination decrease pain significantly compared to fentanyl-tramadol combination. But in regional techniques, pethidine, phenergan and tramadol in combination with perioperative fentanyl shows same result for decreasing pain. Fentanyl is a better analgesics compared to fentanyl+diclofenac combination in perioperative period and in case of postoperative period paracetamol is better effective compared to tramadol HCL in combination with fentanyl
Article Information
51
1773-79
368
1059
English
IJPSR
S. Saha, S. Chakraborty, T. K. Chatterjee* A.K. Bandyopadhyayd, Sayantan Ray and J. Chakraborty
Department of Pharm. Tech., Jadavpur University, Kolkata, West Bangal, India
tkchatterjee_81@rediffmail.com
25 March, 2014
10 February, 2016
09 March, 2016
10.13040/IJPSR.0975-8232.7(4).1773-79
01 April, 2016