PROTECTIVE ACTIVITY OF SHOREA ROBUSTA LEAF AGAINST OXIDATIVE STRESS IN RATSAbstract
Currently there has been an increased interest globally to identify the plant origin with free radical scavenging properties and have great importance as therapeutic agents in several diseases due to oxidative stress. Lipid peroxidation of cellular membranes has also been implicated in various disease processes, including cardiac ischemia-reperfusion injury. In recent years, the use of natural antioxidants present in food and other biological materials has attracted considerable interest due to their presumed safety, nutritional and therapeutic value. Shorea robusta has wide range of pharmacological activity but the cytoprotective activity against oxidative damage has not yet been documented. The present study was investigated the cytoprotective activity of Shorea robusta extract (SRE). The results of the study indicate that the cytoprotective role of SRE may be related to counteraction of free radicals. The mechanism of cytoprotective is to be worked out in future studies.
C. Karthika, M. Chitra and K. Radhika*
Department of Biochemistry, S.T.E.T Women’s College, Mannargudi, Tamil Nadu, India
09 July, 2013
11 October, 2013
17 November, 2013
01 December 2013