PUTATIVE ROLE OF ISATIN DERIVATIVES SYNTHESIS AND THEIR BIOLOGICAL APPLICATIONS- A REVIEW
AbstractIsatin (1H-indole-2,3-dione) and its derivatives represent an important class of heterocyclic compounds that can be used as precursors for drug production. Erdmann1 and Laurent2 first discovered isatin in 1840 as an oxidation product of indigo dye for nitric acid and chromic acid. Isatin is one of the most important heterocyclic compounds. For example, Schiff foundations of isatin are used for their medicinal properties. This review understands a variety of synthetic methods in particular, sandmeyer synthesis, stolle synthesis, and gassman synthesis isatin synthesis. This review reports some of the biological applications of Isatin derivatives such as anticancer, antiviral, antifungal, antioxidant, etc. From these studies, Isatin was established as a promising candidate for further research and investigation in a number of fields.
Article Information
7
2678-2685
1052 KB
675
English
IJPSR
Anurag Sharma *, Vaishali Bhardwaj and Sucheta Singh
Department of Pharmaceutical Chemistry, Mascot College of Pharmacy, 16th Km. Milestone, Pilibhit Road, Bareilly, Uttar Pradesh, India.
anuragrockbly@gmail.com
26 August 2022
04 November 2022
18 November 2022
10.13040/IJPSR.0975-8232.14(6).2678-85
01 June 2023
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