QUALITATIVE, QUANTITATIVE EXPLORATION OF PHYTOCHEMICALS AND DETERMINATION OF ANTIBACTERIAL ACTIVITY OF SARGASSUM WIGHTIIAbstract
Marine carbohydrates play a crucial role in drug development and disease eradication as it is suggested as a promising bioactive material for its various properties. Seaweeds are the marine macroalgal source that contains a large amount of sulfated polysaccharides. Sargassum wightii (S. wightii) is one of the seaweed which possesses a wide range of pharmacological actions. The aim of the present work is to qualitatively quantitatively analyze the phytochemical substances and screen the antibacterial activity of S. wightii. The study is accomplished with chloroform and methanolic extracts of S. wightii. Among this, methanolic extract of S. wightii shows the presence of more phytochemicals and a substantial antibacterial activity. Quantitative analysis showed the presence of flavonoid content more. Antibacterial activity was more for gram-negative bacteria. Analysis of phytochemical substances and antibacterial activity determination reflected significant results. Hence further observations and studies on this macroalgae could bring out promising results in the future for the welfare of mankind.
A. M. Saral * and F. Mathew
Department of Chemistry, School of Advanced Studies Vellore Institute of Technology, Katpadi, Vellore - 632014, Tamil Nadu, India.
01 January 2020
07 April 2020
10 April 2020
01 January 2021