RECENT ADVANCES IN ORAL THIN FILM DRUG DELIVERY SYSTEMS: A REVIEW
AbstractSeveral fast-dissolving drug delivery systems have been designed to address issues like accurate dosing in liquid dosage formulation (suspension, emulation, syrup etc.) and swelling problems in solid dosage form (capsule, Tablet etc.). To fill these gaps fast-dissolving drug delivery system have been designed to address these issues. Biggest advantage of having Oral thin Film is, it can be taken without water, Easy to tackle and carry. Oral thin film formulates with various polymers, plasticizers, active pharmaceutical ingredients, sweetening agents, flavoring agents, coloring agents, stabilizing saliva enhancing agents and thickening agents. The method of preparation for oral thin film were reported are solvent casting, Semisolid casting, Hot melt extrusion, Solid dispersion extrusion and rolling. The current evaluation gives an account of different formulations methods of preparation and quality control of the fast-dissolving oral thin film. Stable drug-type tablets and capsules are inconvenient to administered for many pediatric and geriatric patients.
Article Information
12
1241-1261
857KB
34
English
IJPSR
Pratima Bisen and Surendra Pardhi *
Department of Pharmaceutics, Sardar Patel University Balaghat, Dongariya, Madhya Pradesh, India.
surendrapharma.pardhi64@gmail.com
21 November 2024
17 January 2025
22 January 2025
10.13040/IJPSR.0975-8232.16(5).1241-61
01 May 2025