REVIEW ON SRC KINASES AS A PROMISING PHARMACOLOGICAL TARGET FOR VARIOUS DISEASES

This review explores the multifaceted roles of Src kinases, a subfamily of non-receptor tyrosine kinases, shedding light on their involvement in diverse diseases. Src-family protein tyrosine kinases (SFKs) exhibit widespread expression across various cell types, influencing their behavior and functionality. Src’s presence in distinct subcellular locations, such as plasma membranes, perinuclear membranes, and endosomal membranes, underscores its versatility and potential impact on cellular processes. Research indicates a significant association between SFKs and various disorders, emphasizing their relevance as potential therapeutic targets. The intricate interplay of SFKs in cellular membranes suggests a nuanced role in disease pathogenesis. The comprehensive examination of Src kinase’s involvement in different cellular contexts contributes to a better understanding of its potential implications in disease development. In conclusion, this study underscores the pivotal role of Src kinase and positions it as a promising therapeutic target for addressing a spectrum of illnesses. By elucidating the intricate mechanisms through which SFKs operate in cellular membranes, this review advocates for further exploration of Src kinases as crucial players in disease pathology. Recognizing the diverse roles of SFKs provides a foundation for the development of effective and secure treatments, opening avenues for targeted interventions in diseases where Src kinases play a pivotal role.