ROLE OF MICROWAVE ASSISTED EXTRACTION FOR ISOLATION OF SAPONINS FROM SAPINDUS MUKORROSAI AND SYNTHESIS OF ITS STABLE BIOFUNCTIONALIZED SILVER NANOPARTICLES AND ITS HYPOLIPIDAEMIC ACTIVITY
AbstractThis research emphasis on microwave assisted extraction of fruits of Sapindus mukorrosai. Aqueous fruit extract is subjected for the isolation of saponins, focusing only on higher molecular weight of saponins using dialysis membrane. On treatment of aqueous solution of silver nitrate with isolated saponin, stable silver nanoparticles were rapidly formed. The green synthesized silver nanoparticles were characterized by UV-vis spectroscopy, scanning electron microscope (SEM), energy dispersive X-ray (EDX). The SEM confirms the synthesis of square shape of nanocrystalline particles with the size range of 60-90 nm. The presence of saponins has confirmed by FTIR spectra. These nanoparticle has been subjected for hypolipidaemic activity in animal model. It showed significant reduction in total cholesterol, triglyceride level, HDL and VLDL parameters
Article Information
24
2959-65
533
1749
English
IJPSR
Shilpi Mishra* and Mayank Thakur
Advance Institute of Biotech & Paramedical Sciences, Kanpur, Uttar Pradesh, India
shilpi24mishra@gmail.com
28 February, 2016
26 March, 2016
27 May, 2016
10.13040/IJPSR.0975-8232.7(7).2959-65
01 July 2016
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