SCIENTIFIC VALIDATION OF JAWARISH-E-BISBASA – A UNANI FORMULATIONAbstract
The compound drug Jawarish-e-Bisbasa is a polyherbal Unani formulation. It is used in the ailments of general weakness of the stomach, flatulence in the stomach, indigestion, blind piles and nausea etc. Therefore the scientific validation for development of SOP, pharmacopoeial standards, TLC studies and safety parameter is very much essential to provide the quality medicine to the needy mass. The drug was prepared in different batches at laboratory scale using authenticated nine raw drugs. The present study was aimed to develop the SOP’s for the preparation of drug and to evaluate its pharmacopoeial parameters, estimation of heavy metals, microbial load, aflatoxins and pesticide residues. The obtained physicochemical data will help in laying down SOP’s and pharmacopoeial standards for this drug. Thin Layer Chromatographic studies of the drug will provide the finger prints which will help in quality control and detection of adulteration. The result of quality control parameters such as microbial load, aflatoxins, heavy metals and pesticide residue shows that the drug is free from toxic substances.
Rampratap MeenaD Ramasamy , S Mageswari , Syed Jameeluddin Ahmed , Samsul Arifin, Shamshad Ahmed Khan and Syed Shakir Jameel
Research Officer (Chemistry), Regional Research Institute of Unani Medicine (CCRUM), No. 1, West Madha Church Road, Chennai – 600 013, Tamil Nadu, India
24 April, 2012
14 May, 2012
21 July, 2012
01 August, 2012