SCREENING FOR PHYTOCHEMICAL, FLAVONOID CONTENT, ANTIOXIDANT AND ANTHELMINTIC POTENTIAL OF SIDA SPINOSAAbstract
Background: Sida spinosa (Family: Malvaceae) is a well-known herb, has considerable medicinal significance in the tribal region of Chhattisgarh. Several ethnomedicinal survey reports have been revealed its potential to cure ailments such as skin diseases, diarrhea, gonorrhea, and asthma. Objective: The aim of the present study to screen phytochemical, flavonoid content, antioxidant and anthelmintic potential of Sida spinosa. Methods: Aqueous and ethanolic extracts of Sida spinosa leaves were prepared by the Soxhlet method. The extracts were phytochemically analyzed for alkaloid, flavonoid, tannin, carbohydrate, glycoside, and Phytosterols. Extracts were also tested for flavonoid content, antioxidant potential, and anthelmintic activity using Indian adult earthworm (Pheretima posthuma). Results: The phytochemical screening confirmed the presence of alkaloids, carbohydrates, glycosides, flavonoids, steroids, in the leaves of Sida spinosa. The Present study also reported that ethanolic extract has exhibited significant free radical scavenging capacity and anthelmintic activity as compared to aqueous extract. Conclusion: The present study has evidenced the prominent antioxidant and anthelmintic action of Sida spinosa, which may contribute to the development of an herbal alternative to synthetic drugs for helminthiasis.
University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, Chhattisgarh, India.
26 September 2019
06 November 2019
13 November 2019
01 December 2019