SCREENING OF ANTI-BACTERIAL ACTIVITY OF BROWN SEAWEEDS FROM SOUTH EAST COAST OF INDIAAbstract
Three different species of seaweeds collected from south east coast of India such as Sargassum plagiophyllum, Padina gymnospora and Turbinaria conoides for evaluating anti-bacterial activity against selected gram-positive and gram-negative bacteria. Extracts prepared using solvents namely hexane, ethyl acetate, methanol, and water against human pathogenic strains of Proteus vulgaris, Staphylococcus aureus, Klebsiella pneumonia, Enterobacter aerogenes, Salmonella typhimurium, Yersinia pestis, Shigella fiexneri, Staphylococcus epidermidis and Bacillus subtilis. Gram-negative bacteria showed a lesser zone of inhibition than gram-positive bacteria with various extracts tested. All the three solvent extracts of Turbinaria conoides showed, zone of inhibition for the gram-positive bacteria, Staphylococcus epidermidis over the standard control, with a significant zone in hexane extract. Analysis of GC-MS of Turbinaria conoides hexane extract revealed 14 major and numerous minor phytochemical compounds that have to be fractionated and explored for specific anti-bacterial activity in order to isolate a potential anti-bacterial compound.
K. K. Vennila *, P. S. Chitra, K. Hilda, S. Janarthanan and P. Martin
Department of Zoology, Quaid-e-millath College, Chennai, Tamil Nadu, India.
08 September 2019
23 February 2020
19 April 2020
01 August 2020