SCREENING OF BEHAVIOURAL, MUSCLE CO-ORDINATION & ANXIOLYTIC ACTIVITIES OF METHANOLIC EXTRACT OF SOPHORA INTERRUPTA (BEDD)
AbstractThe aim of this study was to evaluate the behavioural, muscle coordination and anxiolytic activities of methanolic extracts of Sophora interrupta (papilionaceae) in mice. The behavioural, muscle coordination and anxiolytic activities were evaluated by using various models of CNS using mice. Diazepam was used as standard drug for muscle coordination and anxiolytic studies. The extracts were administered orally at 400 mg/kg. The results of the present study indicates that the methanolic extract of Sophora interrupta leaves are effective in inducing a significant protection against behavioural, muscle coordination and anxiolytic activities, as evidenced by various CNS models with respect to control. This study confirmed the behavioural, muscle coordination and anxiolytic activities of this plant as it is used in traditional medicine.
Article Information
30
526-531
376KB
1028
English
IJPSR
K. Veeresh , M. Vijusha , Rajani* and K. Hemamalini
Teegala Ram Reddy College of Pharmacy, Meerpet, Andhra Pradesh, India
rkhemamalini@gmail.com
27 September, 2013
20 November, 2013
16 January, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(2).526-31
01 February, 2014
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