SCREENING OF CYANOBACTERIA STRAINS FROM DELHI AND NCR FOR ANTI-BACTERIAL POTENTIALAbstract
Cyanobacteria or blue green algae have an extraordinary potential of producing secondary metabolites which can be an ultimate source of newer drugs for future. The purified strain Anabaena showed best photoautotrophic growth at 28oC with specific growth and generation time were 0.098 and 10.0 hr respectively. The better biomass production and antibacterial activity on 30th days of culture. 16 cyanobacterial strains collected from different sites of Delhi and NCR (National Capital Region, INDIA) identified as Microcystis, Anabaena, Oscillatoria, Nostoc, Phormidium sps were examined for antibacterial properties. The crude methanolic intracellular extracts of 8 strains showed activity against non-pathogenic Enterobacter aerogens and all 16 given potential against pathogenic Escherichia coli. In which purified Anabaena sps given maximum antibacterial activity against E. coli while Anabaena (Johad) and Microcystis (water tank) from Manesar (Gurgaon, India) against E. aerogens. The same strain from different origin has different antibacterial activity. This interpretation indicates the biosynthesis of bioactive molecules is niche and species specific.
Sachin Chauhan , Ashu Vats , Pooja Dabas, Sonam Kumari , Shweta Tripathi , Naveen Kumar , Indu Malik , N.V.S.R.K. Prasad , Deepali* and K.V. Giri
Department of Life Science, Sri Venkateswara College, University of Delhi, Benito Juarez Road, New Delhi-110 021, India
24 October, 2013
04 December, 2013
16 February, 2014