SCREENING OF MEDICINAL PLANTS FOR EFFECTIVE BIOGENESIS OF SILVER NANO PARTICLES AND EFFICIENT ANTI-MICROBIAL ACTIVITY

Metal nanoparticles have been using as an ingredients in the preparation of complementary medicines to cure different diseases is an age old medicinal practices. The plant based Ayurvedic preparations are preferred by 80% of the world population and WHO is encouraging the green medicine due to its less side effects. Hence an attempt has been made to screen this important medicinal plant for secondary metabolites biogenesis of silver nanoparticles (SNPs) and their antimicrobial efficacy. The stem, roots, stembark and leaves were selected for synthesis of SNPs. The SNPs formation was confirmed with the help of UV-VIS spectroscopy and characterized by AFM. The phytosynthesized SNPs were tested for antibacterial and antifungal activities using paper disc diffusion method. The results indicate that the selected plant revealed that it is source for different secondary metabolites like anthocyanins, emodins, triterpenoids, tannins, saponins, luecoanthocyanins, reducing sugars, flavonoids, lignins, anthroquniones, phenols and glycosides.  But steroids, coumarins, fatty acids and alkaloids are absent.  The SNPs are having more anti microbial efficacy than that of the plant extracts. Moreover the SNPs of selected plant parts are having toxicity towards bacterial species than that of fungal species.  It is concluded that the environmentally benign SNPs synthesized from different parts of Shorea tumbuggaia can be used effectively against bacterial and fungal strains.  The SNPs may have important advantage over conventional antibiotics to which the bacteria got resistance