SEDATIVE AND HYPNOTIC ACTIVITY OF BULBS OF ALLIUM CEPA LINN.Abstract
The onion (Allium cepa L), also known as the bulb onion or common onion, is used as a vegetable and is the most widely cultivated species of the genus Allium. Allium cepa L belongs to the family Lilliaceae. The onion has a wide range of beneficial actions on the body and when eaten (especially raw) on a regular basis will promote the general health of the body. The parameters selected were preliminary phytochemical screening and sedative hypnotic activity by chimney test. The Allium cepa Linn powder was successively extracted with benzene, chloroform, ethylacetate, ethanol and water for the identification of the best solvent. Preliminary phytochemical screening was carried out for all the extracts and maximum chemical constituents were observed in the ethanolic extract. The sedative and hypnotic activity were tested by using ethanolic extract on mice by using chimney test and found to be effective at a dose of mg/kg when compared to the reference standard. In conclusion it can be said that Allium cepa L possess Sedative and hypnotic activity at a dose of mg/kg.
S.V. Mahalakshmi Rampalli*, Rajyalaxmi Gudepu, Md. M. Rabbani and Yasodha Krishna Janapathi
Department of Pharmacology, Sri Sarada College of Pharmacy, Bhongir, Nalgonda-508116, Andhra Pradesh, India
25 July, 2013
12 September, 2013
29 November, 2013
01 December 2013