SELF-EMULSIFYING SYSTEMS: A REVIEWAbstract
Effective delivery of drugs can be made through various routes of administration, and the oral route is considered to be the most convenient for the administration of drugs to patients. Poor aqueous solubility was acknowledged as the main reason for the poor oral absorption of chemical entities. Apart from the conventional solubilization approaches like co-solvency, salt formation, solid dispersion, more recently self-emulsifying drug delivery systems (SEDDS) have been studied in improving the solubility and dissolution rate of poorly water-soluble and lipophilic drugs. SEDDS can be administered orally in soft or hard gelatin capsules or by converting them into tablets using different techniques like adsorption, melt granulation/extrusion and spray drying for improved stability and ease of administration.
K. L. Prasad, G. Vasavi and K. Hari *
Department of Pharmaceutical Technology, Maharajah’s College of Pharmacy, Phool Baugh, Vizianagaram, Andhra Pradesh, India.
02 April 2020
22 July 2020
26 July 2020
01 August 2020