SERUM CALCIUM, INORGANIC PHOSPHORUS AND URIC ACID LEVELS DURING VARIOUS PHASES OF MENSTRUAL CYCLEAbstract
Hormonal changes during the menstrual cycle are well documented but there are very few reports on the changes in serum calcium, phosphorus and uric acid levels in various phases of the menstrual cycle. Therefore, present study was conducted on 50 healthy females in the age group of 18-35 menstruating regularly (cycle length between 25 and 35 days). The study demonstrated that serum calcium levels were significantly (p<0.001) higher in follicular phase than menstrual and luteal phases. Serum inorganic phosphorus levels decreased progressively and significantly (p<0.001) from the menstrual phase to the follicular phase and from the follicular phase to the luteal phase while serum uric acid levels were significantly (p<0.001) lower in luteal phase than the menstrual and follicular phases. These changes in calcium, phosphorus and uric acid in serum may have significance in terms of the normal reference interval, hence necessitate small but significant alterations to the normal reference interval for these analytes in menstruating women.
M. A. Lanje*, A. K. Bhutey, S. R. Kulkarni, U. P. Dhawle and A. S. Sande
Department of Biochemistry, Dr. Panjabrao Deshmukh Memorial Medical College, Amravati, Maharashtra, India
18 October, 2010
21 November, 2010
14 January, 2011
01 February, 2011