SILVER NANOPARTICLES POSSESS ANTI-BIOFILM ACTIVITY AGAINST MULTIDRUG-RESISTANT STAPHYLOCOCCUS SAPROPHYTICUS ATCC 15305Abstract
An example of the human microbiota is Staphylococcus saprophyticus, a gram-positive, non-hemolytic pathogenic bacterium. It’s a prevalent culprit behind simple infections associated with the urinary tract, especially among sexually active young women. It has a high colonization rate in the perineum, rectum, urethra, cervix, and gastrointestinal system and is also quite lethal. Because of their ability to form a biofilm, these bacteria are highly resistant to antibiotics. Thus, unconventional methods, such as the use of silver nanoparticles, have been devised to counteract this type of biofilm. The silver nanoparticles are produced in an environmentally friendly way by utilizing an extract of water from banana peels. UV/Vis, FTIR, SEM, and EDAX are the four methods used to characterize the NPs and validate their production. Using the Screening method and SEM analysis, we show that silver nanoparticles inhibit the growth of Staphylococcus saprophyticus ATCC 15305, the most prevalent bacteria responsible for urinary tract infections.
Sreelekha Das, Sutripto Ghosh, Quazi Sayeed Ahmed, Sharmistha Bhandari and Tamalika Chakraborty *
Department of Life Science, Guru Nanak Institute of Pharmaceutical Science and Technology, Kolkata, West Bengal, India.
31 January 2023
26 March 2023
26 April 2023
01 September 2023