STANDARDIZATION OF KUTAJAGHANA VATI: AN AYURVEDIC POLYHERBAL FORMULATIONAbstract
In order to have a good coordination between the quality of raw materials, in process materials and the final products, it has become essential to develop reliable, specific and sensitive quality control methods using a combination of classical and modern instrumental method of analysis. Standardization is an essential measurement for ensuring the quality control of the herbal drugs. “Standardization” expression is used to describe all measures, which are taken during the manufacturing process and quality control leading to a reproducible quality. Kutajaghana vati is official in Ayurvedic formulary of India and is prescribed for the treatment of diarrhea, Irritable bowel syndrome. It is a polyherbal preparation containing two ingredients. In this research paper, an attempt has been made to develop standardization methods of Kutajaghana vati. In-house preparation and the marketed drug have been standardized on the basis of macroscopic, microscopic, physic-chemical parameters and Thin Layer Chromatographic study (TLC). The set parameters were found to be sufficient to evaluate the Vati and can be used as reference standards for the quality control/quality assurance.
Rashmibala Sahoo* and Pramoda Kumar Swain
State Drug Testing & Research Laboratory (ISM), Govt. Ayurvedic Hospital Campus, BJP Nagar, Bhubaneswar-751014, Orissa, India
17 June, 2011
20 July, 2011
28 September, 2011
01 October, 2011