STUDY OF ANALGESIC ACTIVITY OF LITSEA GLUTINOSA (L.) ETHANOLIC EXTRACT ON SWISS ALBINO MICEAbstract
Aim: Litsea glutinosa (L.) a medicinal plant is popularly used as herbal remedy for various ailments. But the scientific basis for its medicinal use especially in pain and inflammation remains unknown. Therefore, the present study was designed to evaluate analgesic potential of the ethanolic extract of the bark of the plant.
Approach: The analgesic activity of standard tramadol HCl was determined for its central pharmacological actions using hotplate method in mice. Simultaneously the ethanolic extract was also investigated for its analgesic action.
Results: The extract, at the dose of 100 and 300 mg/ Kg, has shown a significant (p<0.05) increase in pain threshold in hotplate, as compared with control group.
Pattari Lohitha*, I. S. Muchandi, V. N. M. S. Haricharan K., N. Himabindu, G. Mamatha, C. H. Tejaswi, K. Ramanjaneyulu and S Vanitha Sagar
Vishnu Institute of Pharmaceutical Education and Research (VIPER), Vishnupur, Narsapur, Medak Dist. Hyderabad (AP), India
23 May, 2010
25 August, 2010
30 August, 2010
15 September, 2010