STUDY OF THYROID DYSFUNCTION IN TYPE II DIABETES MELLITUSAbstract
Diabetes Mellitus (DM) has emerged as a common endocrine disorder in the world and the prevalence of thyroid dysfunction is increasing at the same time. The thyroid hormones control insulin secretion. In hypothyroidism there is a reduction in glucose-induced insulin secretion by beta cells, and during thyrotoxicosis the insulin resistance will be increased. Type 2 diabetes mellitus patients with subclinical hypothyroidism are at risk of complications like neuropathy and cardiovascular events. Hence, there is a need to detect subclinical hypothyroidism in diabetic patients.50 type II DM patients were screened for thyroid function studies viz T3, T4 & TSH. 50 age and sex matched healthy volunteers were treated as controls and the results were correlated with fasting blood glucose levels and lipid parameters. The results showed a significant difference among the controls and the patients. It may be concluded from this study that there is hypothyroidsm in DM patients.
Sarguru Datchinamoorthi *, Naveena Rathanavel, Balaji Rajagopalan and R. Vanaja
Department of Biochemistry, Shri Sathya Sai Medical College and Research Institute, Chennai, Tamilnadu, India.
25 April, 2016
31 May, 2016
13 June, 2016
01 September 2016