SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NOVEL SEMICARBAZONE DERIVATIVES CONTAINING QUINOXALINE MOIETYAbstract
Various 1-(substituted benzylidene)-5-(3-hydroxyquinoxaline-2-yl) carbonohydrazide were synthesized starting from orthophenylenediamine. Structures of all the compounds were confirmed on the basis of spectral analyses. All the newly synthesized compounds were screened for anticonvulsant activity. Some of the compounds showed significant anticonvulsant activity with no neurotoxicity.
Rakesh Sahu*, Sonal Tiwari, Jay Kumar Chandra and Prabhat Kumar Patel
Shri Rawatpura Sarkar Institute of Pharmacy, Kumhari-490042, Chhattisgarh, India
11 July, 2012
29 October, 2012
31 October, 2012