SYNTHESIS AND ANTIMICROBIAL STUDIES OF SOME NEW HALOGENATED ISOXAZOLINE DERIVATIVES
AbstractA series of some new Isoxazoline derivatives derived from 3-(4’-dimethylamino-phenyl)-1-(2-hydroxyphenyl)-Propenone(chalcone) derivatives using hydroxylamine hydrochloride is reported. These newly synthesized compounds were screened for their antimicrobial potencies which reflect moderate to good activity against different strains of bacteria and fungi employed. The promising feature of this reaction is mild reaction condition and excellent yield with high purity of compounds synthesized. All the synthesized compounds were confirmed by IR, 1HNMR and Mass
Article Information
43
1183-1185
534KB
1172
English
IJPSR
M.M. Kendre, Shahid Shaikh, N.N. Shah and M.A. Baseer*
Organic Chemistry Research Laboratory, Yeshwant Mahavidyalaya, Nanded-431602, Maharashtra, India
dr.baseer.nanded@gmail.com
30 November, 2012
29 January, 2013
27 February, 2013
http://dx.doi.org/10.13040/IJPSR.0975-8232.4(3).1183-85
01 March, 2013