SYNTHESIS AND BIOLOGICAL SIGNIFICANCES OF 1, 2, 4-TRIAZOLE AND ITS DERIVATIVES: A REVIEWAbstract
In the last few decades, to synthesize the different new heterocyclic compounds along their derivatives which were evaluated for their biological activities as antimicrobial, antiviral, antitumor, anticonvulsant, antifungal, the triazole moiety seems to be very small but in the biological profile has attracted the attention of many researchers to explore this skeleton to its multiple potential against several activities. In this review we provides a brief response of the medicinal chemistry of 1, 2, 4-triazole and its derivatives. A literature survey of procedures for the preparation of 1, 2, 4-triazole and 1, 2, 3-triazoles is presented by generalized synthetic method.
Mukhtyar S. Saini* and Jaya Dwivedi
Department of Chemistry, Govt. G. M. Science College , Jammu-180 001, Jammu and Kashmir, India
26 March, 2013
02 May, 2013
15 July, 2013
01 August, 2013