SYNTHESIS AND CHARACTERIZATION OF 3-[(5-(2-NITROPHENYL)-1, 3, 4-OXADIAZOL-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONE
AbstractQuinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. The present survey aims to achieve the synthesis of quinazolinones and their derivatives of specific pharmacological properties. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, antihistaminic, anticancer and so on. At present some novel quinazolinone derivatives are synthesized and characterized by IR, H1 NMR, MASS Spectral studies.
Article Information
57
4954-4958
635
1595
English
Ijpsr
Ramesh Dhani
Department of Pharmaceutical Chemistry, Oil Technological Research Institute, Jawaharlal Nehru Technological University Anantapur, Andhra Pradesh, India
dhaniramesh1@gmail.com
28 August, 2012
03 October, 2012
29 November, 2012
http://dx.doi.org/10.13040/IJPSR.0975-8232.3(12).4954-58
01 December, 2012
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