SYNTHESIS AND CHARACTERIZATION OF BIOLOGICALLY ACTIVE COMPOUND E-2-((2-AMINO PYRIDINE-3-YL) METHYLENE AMINO) ETHANE THIOL AND ITS METAL COMPLEXESAbstract
A new physiologically active compound E-2-((2-amino pyridine-3-yl) methylene amino)ethane thiol derived from the condensation of Cysteamine and 2-amino Pyridine 3-Carbaldehyde was synthesized and characterized by spectral techniques like IR, UV-Vis,1H- NMR, TG-DTA, ESR, CHN analyses. The complexes were further screened for their biological activity at Nishka labs and Nickel and Cobalt complexes were found to be potent antibacterial agents. From the above analysis it was found that the ligand behaves as a neutral ligand with N: N: S:N:N donor sequence for octahedral complexes.
A. Khamamkar , S. Gajula and V. R. Pallapothula *
Department of chemistry, University college of Science, O.U, Hyderabad, Telangana, India
22 March, 2016
11 May, 2016
31 May, 2016
01 August 2016