SYNTHESIS, CHARACTERISATION AND ANTIFUNGAL STUDIES OF Cu (II) HALIDE COMPLEXES OF SOME STERYL DERIVATIVES OF SUBSTITUTED BENZIMIDAZOLESAbstract
Complexes of Copper (II) halides with steryl derivative of 2- methylbenzimidazole (stmbz), 2-ethylbenzimidazole (stebz) and 2-benzylbenzimidazole (stbbz) of composition CuL2X2 (L = stmbz, stebz and stbbz and X = Cl, Br) have been prepared and characterised. The magnetic susceptibility e.p.r. data, electronic absorption pattern and i.r. spectral studies of complexes indicated distorted octahedral environment of ligand around copper (II) atom. Steryl derivatives and their copper (II) complexes were screened for their antifungal activity in dilute aqueous ethanolic media where bromide complexes show higher antifungal activity than free ligands.
L.K. Mishra* and Madhu Bala
Professor, Department of Chemistry (Retd.), Patna University, Patna- 800 005, Bihar, India
07 April, 2013
24 June, 2013
26 August, 2013
01 September, 2013