SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME TARTARATES AND TRANSITION METAL COMPLEXES
AbstractMetal complexes having two or more different metal ions not only possess excellent catalytic applications but also have many biological activities. In the present work, some ligand tartarate based mixed transition metal complexes of type [MxMI1-x (C4H4O6)]. XH2O [Where M and MI are Cu and Ni, and x= 0.2, 0.4, 0.6 and 0.8] have been successfully synthesized and were characterized by different sophisticated analytical techniques such as elemental analysis, FT-IR, TGA and XRD. From the analytical data; it was observed that all the complexes exhibited 1:1 (methyl: ligand) ratio. IR data shows that the ligand co-ordinates with metal ions in a bidentate manner through the two oxygen atoms. Thermal analysis shows the degradation pattern of the complexes. The synthesized metal complexes were then tested in vitro for biological activities against Bacillus subtilis, Staphylococcus Aureus, and Escherichia coli to assess their antibacterial and antifungal effect. Some of them showed promising antimicrobial activity.
Article Information
58
1557-1565
813KB
1202
English
IJPSR
S.S. Pawar , C.S. Patil , V.B. Tadke , S.M. Vhankate , S.A. Dhanmane , G.R. Pathade and R.P. Pawar*
Department of Chemistry, Deogiri College, Aurangabad, Maharashtra, India
rppawar@yahoo.com
20 November, 2013
04 January, 2014
26 March, 2014
http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1557-65
01 April, 2014
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