SYNTHESIS, CHARACTERIZATION, DNA-BINDING, PHOTOCLEAVAGE AND ANTI-MICROBIAL STUDIES OF COMPLEX [Ru(4-ETHYL- PYRIDINE)4(DPPZ)]2+
AbstractThe new Ru (II) complex [Ru(4-Et-py)4(dppz)]2+ (dppz = dipyrido phenazine) have been synthesized and characterized by different analytical techniques like elemental analysis, LC-MS, 1H NMR , 13C NMR. The interaction of this complex with calf thymus DNA has been explored by U.V. absorption spectroscopy, Fluorescence measurements, and viscosity measurements. Their photocleavage behavior towards pBR 322 and anti-bacterial properties of this complex was also investigated. The experimental results show that the complex binds with DNA by intercalation mode.
Article Information
25
2265-2273
556KB
1277
English
IJPSR
Padmaja Naishadham and S. Satyanarayana*
Department of Chemistry, Osmania University, Hyderabad, Andhra Pradesh, India
tapadmaja@gmail.com
06 February, 2013
20 March, 2013
25 May, 2013
http://dx.doi.org/10.13040/IJPSR.0975-8232.4(6).2265-73
01 June, 2013
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