SYNTHESIS OF SOME- 6- SUBSTITUTED- 6H- PYRROLO [3, 4-D] PYRIDAZINE DERIVATIVES AND THEIR EVALUATION FOR IN-VIVO ANTI-CONVULSANT ACTIVITY IN ALBINO RATSAbstract
Present studies on the synthesis and evaluation of anticonvulsant activity of some 6- Substituted- 6H- Pyrrolo [3, 4-d] Pyridazine derivatives. In the preliminary screening for anticonvulsant activity in albino rats, all the synthesized compounds were found to be active, even more than standard at dose 50mg/kg body weight.
Kamta P. Namdeo*, Alok S. Thakur and Surendra H. Bodakhe
SLT Institute of Pharmaceutical Sciences, G. G. University, Bilaspur, Chhattisgarh, India
22 December, 2011
24 February, 2012
28 March, 2012
01 April, 2012