SYNTHESIS, SPECTROSCOPIC, THERMAL STUDIES AND BIOLOGICAL ACTIVITY OF A NEW SULFAMETHOXAZOLE SCHIFF BASE AND ITS COPPER COMPLEXES
AbstractA new Sulfamethoxazole Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzenesulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated on the basis of Physiochemical methods. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The IR spectra suggest that the ligand act as tridentate (from oxygen and two nitrogen atoms) donor. Also the biological activity of the Schiff base and its Cu complex were studied.
Article Information
15
3143-3148
1042
1525
English
Ijpsr
M. A. El-Nawawy, R. S. Farag, I. A. Sabbah, and A. M. Abu-Yamin*
Department of Chemistry, Faculty of Science Al-Azhar University, Cairo, Egypt
05 August, 2011
17 October, 2011
10 November, 2011
://dx.doi.org/10.13040/IJPSR.0975-8232.2(12).3143-48
01 December, 2011