SYNTHESIS, SPECTROSCOPIC, THERMAL STUDIES AND BIOLOGICAL ACTIVITY OF A NEW SULFAMETHOXAZOLE SCHIFF BASE AND ITS COPPER COMPLEXESAbstract
A new Sulfamethoxazole Schiff base (E)-4-(4-methoxybenzylideneamino)-N-(5-methylis-oxazol-3-yl) benzenesulfonamide (C18H17N3O4S), and its copper complex were synthesized and the structures elucidated on the basis of Physiochemical methods. The studies indicate an octahedral structure for the complexes with the (C22H27N3O10SCu) formula. The IR spectra suggest that the ligand act as tridentate (from oxygen and two nitrogen atoms) donor. Also the biological activity of the Schiff base and its Cu complex were studied.
M. A. El-Nawawy, R. S. Farag, I. A. Sabbah, and A. M. Abu-Yamin*
Department of Chemistry, Faculty of Science Al-Azhar University, Cairo, Egypt
05 August, 2011
17 October, 2011
10 November, 2011
01 December, 2011