THE ANTICANCER ACTIVITY OF BIOACTIVE COMPOUNDS FROM MEDICINAL PLANTS: AN REVIEWAbstract
Cancer is a serious health concern in both developed and developing nations. Cancer causes due to unwanted growth of cells and irregular cell division. Medicinal plants have been used by village folk from ancient times. The plants contain various bioactive compounds that can be used for treating cancer. Some of the phyto compounds isolated from plants have shown promising results; these include curcumin, vinblastine, vincristine, camptothecin. The various phytochemicals like terpenoid, flavonoids, and coumarins were also found promising in treating cancer. A lot of plants based compounds are under trial resulted in good responses. Around 17 different plant families, members with their active constituents reported for targeting cancer pathways were summarized. In this review, various medicinal plants which are reported for anticancer drug discovery were listed and mentioned for their mechanisms of action, such as CDK inhibitor, roles of apoptosis, and angiogenesis in cancer pathways. These plants are very useful in various research studies or for research purposes; these plants seek considerable attention.