THERAPEUTIC CARRIERS FOR THE VAGINAL DELIVERY OF ANTI-HIV DRUGAbstract
HIV is a pandemic disease that is rapidly spreading across the world. The current review’s objective is to present how comprehensive various advanced anti-HIV drug delivery systems are. The use of a new drug delivery system helps in overcoming the challenges of dosage form growth, such as drug instability, insolubility, and restricted entrapment. Several delivery routes for ARV therapy have been identified, including trans dermal, mucosal (vaginal, rectal, buccal, etc.) and lymphatic delivery, utilizing novel systems such as nanoparticles, vesicular systems (liposomes, niosomes, ethosomes, emulsomes), micellar assemblies and so on. This review examines the potential of novel drug delivery systems for the prevention, treatment of retroviral infections, approaches and applications of novel drug delivery systems for Anti-HIV agents.
Nitin Martandrao Mehetre * and Inderbir Singh
Formulation Research and Development, Hetero Labs Limited, Village: Kalyanpur, Chakkan Road, Baddi, Tehsil Baddi, District Solan, Himachal Pradesh, India.
08 March 2021
14 June 2021
21 June 2021
01 February 2022