THERAPEUTIC POTENTIAL AND CHARACTERIZATION OF SENNA ALATA: AN ETHANO-MEDICINAL PLANTAbstract
Senna alata is an effective novel pharmaceutical medicinal plant. The hot extraction method was used to prepare methanol and ethanol extracts of leaves. The extracts were further evaluated to study Antimicrobial potential, phytochemical analysis, FTIR, and Antioxidant activity. The FTIR analysis showed various functional groups that served as secondary metabolites and responsible for antimicrobial activity. The antimicrobial activity of the extract may be due to the presence of secondary metabolites like alkaloids, terpenoids, phenols, saponins, flavonoids, glycosides and tannins. The Senna alata leaves were evaluated for antimicrobial activity against clinically important bacterial strains such as E. coli, B. cereus, B. subtilis, S. aureus, P. aeruginosa, P. fluorescens, and fungi strain namely A. niger by agar well diffusion method. The ethanolic extract of the leaves of Senna alata showed the highest antioxidant activity. S. alata has a great antimicrobial ability which needs to be intensively discussed further.
Prajakta Y. Pachorkar * and Sunita H. Patil
Department of Microbiology, K. R. T. Arts, B. H. Commerce and A. M. Science College, Gangapur Road, Nashik, Maharashtra, India.
01 October 2020
01 March 2021
23 June 2021
01 September 2021