THERAPEUTIC POTENTIAL OF MEDICINAL PLANTS IN TREATMENT OF ANXIETY IN CONTEXT TO NEUROTRANSMITTER: AN OVERVIEWAbstract
Anxiety is a negative emotional state marked by tension, unease, and emotions of concern and fear. Across the globe, women are more likely than males to suffer from anxiety disorders. Insomnia, cold or sweaty hands and/or feet, shortness of breath, an inability to be steady and calm, dry mouth, numbness or tingling in the hands or feet, nausea, abdominal discomfort, dizziness, pins and needles, feelings of losing control, heart palpitations, pins, and needles are just a few symptoms of anxiety disorders. Many systems indicate that when someone is anxious, they exhibit a variety of cognitive, physiological, and behavioral symptoms. Anxiety is brought on by aberrant chemoreceptor responsiveness and unusual neurochemical behavior. Many neurotransmitters, including gamma-amino butyric acid, serotonin, dopamine, noradrenaline (norepinephrine), glutamate, and others, are involved in anxiety. Some have an excitatory or an inhibitory effect. Several promising medications that may be helpful in the treatment of anxiety disorders have been identified via research in the field of herbal pharmacology. Unfortunately, there hasn’t been a thorough examination of plant-based anxiolytics that focuses on their mode of action. Thus, our goal was to present a thorough narrative evaluation of plant-based medications with preclinical evidence of anxiolytic action.
Dhara Parekh *, Vipul Gajera and Tanvi Desai
Department of Pharmacology, Shree Naranjibhai Lalbhai Patel College of Pharmacy, Umrakh Surat, Gujarat, India.
10 March 2023
16 May 2023
31 May 2023
01 November 2023