TO INVESTIGATE THE EFFECTS OF GINGER-JUICE (ZINGIBER OFFICINALE ROSCOE) ON AMPHETAMINE-INDUCED LOCOMOTOR ACTIVITY IN RATAbstract
To investigate the effects of ginger-juice (Zingiber officinale roscoe) on amphetamine-induced locomotor activity in rat. Methods: (A) Albino rats (n=6-12) were administered G.J at the single doses (4 ml/rat, p.o) as single administration (acute) and chronic treatment over period of 7 days. Following this assessment was done. Effect of treatment with G.J acutely and chronically (7days) administered, was assessed. Parameters used during assessment were locomotor activity. Results: The ginger-juice treatment of acute and chronic (4ml/rat for 7 days) and amphetamine-induced locomotor activity has not produced any effect on any parameter of the loco motor activity Conclusion: Ginger administered itself did not affect loco motor activity as well as amphetamine-induced enhancement of loco motor activity.
S. S. Prasad *, R. R. Pathak, S. K. Vajpeyee and V. H. Bhavsar
Department of Pharmacology, GMERS Medical College, Gandhinagar, Gujarat, India
01 August, 2015
18 September, 2015
13 November, 2015
01 February, 2016