TREATMENT OUTCOME OF TUBERCULOSIS PATIENTS ON DOTS THERAPY FOR CATEGORY 1 AND 2 AT DISTRICT TUBERCULOSIS CENTRE

Background: India is highest tuberculosis (TB) burden country accounting for approximately 20% of global TB burden. To tackle this problem, Revised National Tuberculosis Control Programme (RNTCP) based on the DOTS (Directly Observed Treatment Short course) strategy has been made available in the entire country by March 2006.  Present study describes the achievements under RNTCP in terms of treatment outcomes, smear conversion rate and evaluation of risk factors for unsuccessful treatment outcome at district tuberculosis centre. Objectives: Treatment outcome of tuberculosis (TB) patients on DOTS (category 1& 2) and evaluation of predictors for unsuccessful outcome. Methodology:  A record- based retrospective study; analysis of cases registered for treatment for Cat -1 & 2 at district tuberculosis centre during 2013 & 2014 was done. Data regarding demographic profile, TB type & categories, investigation, treatment outcome and co morbidity were recorded. Data were analyzed and appropriate statistical test was done using Epi info 7, CDC. Result: Out of 1340 registered cases, 1081 (80.67%) were of cat1 and 259 (19.33%) were of cat-2 TB.  Majority patients (66.19%) were in 15-44 years of age group. Ratio of Male to female was 2.45: 1 while pulmonary TB to extrapulmonary TB was 3.75:1. Cure rate of whole cohort was 90.29%, while defaulter rate, death rate, treatment failure and transferred out cases were 2.31%, 4.10 %, 1.49% and 1.79% respectively. Unsuccessful outcome was significantly associated with age ≥65 years and those who lost weight during treatment. Conclusion: Target norm set by RNTCP was achieved at district TB centre.