UNDERSTANDING THE EVIDENCES AVAILABLE FOR USE OF TRANSDERMAL PATCHES IN THE TREATMENT OF ASTHMA – A REVIEWAbstract
Transdermal drug delivery systems (TDDS) offers a route that by-passes the gut and hence they are more convenient. They are also non-invasive and safer than the other alternatives. The transdermal or the adhesive patches are used to deliver a specific quantity of drug in a controlled release manner through skin for over a long period of time. There are many types of patches like the matrix, membrane, reservoir, micro reservoir etc. These patches have been in use to deliver many classes of drugs like analgesics, anti-pyretics, anti-diuretics, anti-asthmatics, etc. There are many anti-asthmatic products that are available in the form of transdermal patches internationally like the tulobuterol, salbutamol, ketotifen, etc., but the question is about their usage and availability. The primary aim of this review is to understand the availability of evidences for and against the use of TDDS for asthma. Most studies, both in vivo and in vitro, and both as add-on and as a monotherapy have yielded positive results.
Sam Johnson Udaya Chander J., T. Akelesh and A. Anandhasayanam *
Department of Pharmacy Practice, JKKMMRF College of Pharmacy, Vattamalai, Komarapalayam, TN, India
18 September, 2015
03 December, 2015
08 February, 2016
01 March, 2016