UNRAVELING THE POTENTIAL, A COMPREHENSIVE ANALYSIS OF COMBINATORIAL CHEMISTRY
AbstractIn the pharmaceutical industry, combinatorial chemistry has emerged as a novel approach, facilitating the synthesis of multiple compounds simultaneously rather than focusing on individual compound. The quick production of the chemical means that this technology reduces the time and expense involved in drug research. In this review article, the topic of combinatorial chemistry is discussed in general terms, along with the concepts of combinatorial libraries, methodologies and applications. This technique significantly lowering the cost involved in new drug research and increases the chances of finding new lead molecules. Most commonly used combinatorial techniques are solid phase synthesis, Parallel synthesis, mixed combinatorial synthesis and solution phase synthesis. Combinatorial chemistry is useful for the efficient detection of big molecules as well as the production of tiny molecules and peptides. The aim of this project is to give a fundamental overview of combinatorial chemistry, outlining the evolution of key methods and a few applications.
Article Information
5
2629-2634
882 KB
197
English
IJPSR
K. I. Anoob Kumar *, M. L. Lal Prasanth, M. Archana and C. Vignesh
Department of Pharmaceutical chemistry, Dr. Moopen’s College of Pharmacy, Naseera Nagar, Meppadi (PO), Wayanad, Kerala, India.
anoobkumarki@gmail.com
28 February 2024
05 August 2024
12 August 2024
10.13040/IJPSR.0975-8232.15(9).2629-34
01 September 2024
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