UV-SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF TELMISARTAN IN BULK AND TABLET DOSAGE FORMAbstract
A simple, precise and accurate UV spectrophotometric method has been developed and validated for the estimation of Telmisartan in bulk and tablet dosage form. The spectra of Telmisartan in 0.1 N NaOH and distilled water (20:80) shows λmax at 234 nm and estimation was carried out by A (1% 1cm) and by comparison with standard. Calibration graph was found to be linear (r2= 0.999) over the concentration range of 2-10 μg/mL. The proposed method was validated for its accuracy, precision, specificity, ruggedness and robustness. The method can be adopted in its routine analysis.
Sonali D. Rathod*, P.M. Patil, Santosh S.A. Waghmare and P.D. Chaudhari
Department of Pharmaceutical Chemistry, Modern College of Pharmacy, Nigdi Pune, Maharashtra, India
22 June, 2012
17 July, 2012
26 September, 2012
01 October, 2012