Posted by admin on Jan 31, 2024 in |
Introduction: Urinary tract infection is the most frequent infection reported worldwide till now. To better understanding regarding epidemiology and emerging antimicrobial resistance among bacterial uropathogens, we studied the demographic distribution and antibiotic susceptibility pattern of microorganisms causing UTI in our local hospital-based study. Materials and Methods: We analysed the retrospective data of laboratory confirmed UTIs, from January 2017 to December 2021. Causative agents of UTI, along with their demographic profile, distribution and their antibiogram was determined by using conventional methods. On the basis of that, 5-year multiple antibiotic resistance index was calculated to determine the resistance pattern of isolated bacterial uropathogens. Results: During study period, total 9426 samples were received. Out of which, 1133 (12.01%) showed significant bacteriuria with monomicrobial growth. With 64.17% isolation from female patients with predominance age group 16-60 years. From 1133 positive isolates, gram negative and gram positive isolates were reported in 298 (26.30%) and 835 (73.69%) isolates respectively, with predominance of E. coli (52.25%) followed by Enterococcus spp. (18.36%) Klebsiella spp. (8.21%). Multiple antibiotic...
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Posted by admin on Dec 31, 2023 in |
Avian salmonellosis is a large group of acute or chronic diseases of birds caused by different species of the genus Salmonella. It is a problem of economic concern for all phases of the poultry industry, from production to marketing. The main aim of this study is to investigate the incidence of Salmonella species in the feed and environment of open-system poultry farms. A total of 46 samples were taken from six poultry farms, layers and broilers. The samples include poultry feed from feeders (23 samples) and litter (23 samples). Isolation of Salmonella was carried out in a selective classical medium (DCA) after enrichment in Selenite-F broth. Four Salmonella isolates represent 5% of total samples were recovered; three isolates (75%) from litter samples and one isolate (25%) recovered from water samples; no Salmonellae were recovered from feed samples. All isolates were identified at the species level using cultural characteristics and biochemical reactions. An antimicrobial sensitivity test for the four Salmonella isolates was carried out. Each isolate was tested to 10...
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Posted by admin on Nov 30, 2023 in |
Consistently the preparation of transition metal complexes of β-diketones has been (and it still is) an area of the highest interest for inorganic and organic chemists, as can be inferred considering the quantity and diversity of research developed in this field. 1,3- Diketones are wide range of valuable molecules including several types of carbocycles and heterocycles hence have high interest. In fact, excessive amount of therapeutical uses are associated with these 1,3- Diketone compounds. The present work is based mainly on the ultrasound irradiation synthesis of various β-diketone ligands and their Fe (III) complexes. At ambient temperature, the clinically active and functionalized various β-diketones has been synthesized from Baker–Venkataraman transformation and its Fe (III) complexes has been prepared and characterized by physical, spectral and analytical data. The different spectroscopic analysis like Mass, 1H-NMR, 13C-NMR, IR, UV and elemental analysis were done. The functionalized beta-diketones showed a certain behaviour and behaved as bidentate ligand and co-ordinate with the transition metal atom through beta-diketo system. The complexes have general formula [ML2]....
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Posted by admin on Nov 30, 2023 in |
An attempt was made to identify actinomycete strains of the South coastal region of Andhra Pradesh, India along with the study of their antimicrobial potential. Among the 50 actinomycete strains isolated, one strain (VLS-2) showed strong antimicrobial activity against Gram-positive and Gram-negative bacteria as well as fungi. It was identified as Kocuria assamensis based on morphological, biochemical, physiological as well as molecular characteristics. ISP-1 medium supplemented with sodium chloride @ 7% maintained at pH 7.0 supported the maximum yield of secondary metabolites by the strain when incubated at 35oC for six days. Production of antimicrobials by the strain varied significantly with different carbon and nitrogen sources. The present study reveals the potentiality of actinomycete strains isolated from South-coast of Andhra Pradesh, India which shows further scope to investigate their novel bioactive compounds by employing both natural product chemistry and modern biotechnological...
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Posted by admin on Oct 31, 2023 in |
Annona squamosa (sugar apple) is commonly cultivated in tropical South America occasionally in southern Florida as well as in Jamaica, Puerto Rico, Barbados, and dry regions of Australia. It was growing in Indonesia early in the 17th century and has been widely adopted in southern China, tropical Africa, Egypt, and the lowlands of Palestine. This plant is a small well-branched tree or shrub that bears edible fruits called sugar-apples, species of the genus Annona and a member of the family Annonaceae is traditionally used for the treatment of epilepsy, dysentery, cardiac problem, warm infection, constipation, hemorrhage, antibacterial infection and also has anti-tumor activity. Especially the seeds have another important effect they are medically useful to show many therapeutic activities such as anticancer, and CNS depressant. Hence the present study was taken to test the antimicrobial activity of seeds of Annona squamosa and microbes such as Staphylococcus aureus and Salmonella typhi. The evaluation of the antimicrobial activity of the seed extracts of Annona squamosa was done with methanol using the...
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