Posted by admin on Dec 1, 2014 in |
Some new Sb(III) and As(III) complexes of N∩S donor ligands N’-[1-(2-oxo-2H-chrome-3yl-ethylidene] – hydrazinecarbodithionic acid methyl ester (L1H) and N’ – [1-(2-oxo-2H-chrome-3yl – ethylidene] -hydrazinecarbodithionic acid benzyl ester (L2H) have been synthesized. All the synthesized compounds were characterized by elemental analyses, melting point determinations and a combination of electronic, IR, 1H NMR, and X-ray diffraction spectroscopic techniques. These studies showed that the ligands coordinated to organoantimony and organoarsenic in a monobasic bidentate manner through sulfur and nitrogen donor system. Thus, tetra and pentacoordinated environments around the antimony and arsenic atom have been proposed. In order to evaluate the effect of metal ions upon chelation, both the ligands and their complexes have been screened for their antimicrobial activity against the various pathogenic bacterial and fungal strains. The results indicate that the metal complexes are more potent antimicrobial agents than the parent ligands. Further, the ligands and their corresponding metal complexes have been tested for their pesticidal activity against the Corcyra cephalonica. The results of pesticidal screening are quite...
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Posted by admin on Dec 1, 2014 in |
The aim of this work was to investigate of the antimicrobial and antioxidant potentials of methanol extracts from Ficus carica. Methanol extracts were screened for antimicrobial activity against different species of Gram positive andGram negative bacteria and one yeast. The methanol extract of Ficus carica showed maximum inhibition zone of 10 mm against Listeria monocytogenes. In addition to, the plant extracts were tested against the stable DPPH (2, 2-diphenyl-1-picryl-hydrazyl-hydrate) free-radical. Trolox was chosen as a standard antioxidant. Finally, the methanol extract displayed a strong antioxidant activity (Trolox equivalent= 1.33 mM). Ficus carica methanol extracts have antimicrobial and antioxidant...
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Posted by admin on Nov 1, 2014 in |
A facile synthesis of novel 2-amino-1,2-dihydroisoquinoline-3(4H)-one and their amide derivatives (6a-o) through sydnone intermediate (3) was derived from tetrahydroisoquinoline-3-carboxylic acid (1) and various substituted phenyl acrylic acid derivatives (5a-o) in short reaction time with good yield. The structure of all novel synthesized compounds was established based on Mass, 1H NMR, 13C NMR, IR spectral data and Single crystal X-ray study (6e). All the synthesized compounds were evaluated for their antimicrobial and antioxidant...
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Posted by admin on Nov 1, 2014 in |
Present investigation deals with the evaluation of the antimicrobial activity of extracts of Jatropha gossypifolia Linn., Sapium sebiferum (L.) Roxb., Kirganelia reticulata (Poir) Baill., Phyllanthus fraternus Webster and Pedilanthus tithymaloides (Linn.) Poit. against Escherichia coli, Proteus vulgaris, Staphylococcus aureus and Bacillus cereus and Trichophyton mentagrophytes and T. rubrum. The antibacterial activity was tested by the disc diffusion method and the antifungal (antidermatophytic) activity by the method of Abubacker et al. It was observed that only DMSO extracts of the leaves of K. reticulata and the flowers of P. tithymaloides inhibited the growth of P. vulgaris and S. aureus with MIC at 200 mg ml–1. The extracts did not inhibit the growth of T. mentagrophytes and T. rubrum. The phytochemical analysis of these extracts indicated that the tannin and saponin contents were highest in the leaves of K. reticulata (6.0 and 12.04 % respectively) whereas, the flavonoid and steroid and triterpenoid contents were highest in theflowers of P. tithymaloides (41.20 % and 46.74 %). The MIC values of extracted tannins...
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Posted by admin on Nov 1, 2014 in |
Complexs of Fe, Cu and Zn have been prepared by reacting metal chloride\sulphate with p-hydroxyacetophenone thiosemicarbazone, p-fluoroacetophenone thiosemicarbazone, p-bromoacetophenone thiosemicarbazone as ligands and their complexes were screened for their IR, NMR, and antifungal and antibacterial studies. . Acetophenone thiosemicarbazone ligands were prepared by the reaction of substituted acetophenone with thiosemicarbazone in the presence of hot ethanol. All the transition-ligands 1:2 complexes have been isolated in the solid state, are stable in air, and characterized on the basis of their elemental and spectral data. They were found to be active against influenza, protozoa, small pox, and certain kinds of tumor. Their metal complexes were used, in various biological systems, polymers, dyes, anti-inflammatory, analgesic and anti-oxidative action. The Schiff bases and their metal complexes were used in various biological activities such as antimicrobial, antifungal, antiviral, insecticides, and antitumor...
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