Posted by admin on Jan 1, 2012 in |
Schiff Base derivatives are important class of compounds. They possess different types of Biological activities like antibacterial, antiviral, anti HIV, antifungal etc. Schiff base derivatives are prepared by the condensation of aldehyde and amine and these compounds are characterized by chemical and instrumental methods. Their important biological properties have been...
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Posted by admin on Jan 1, 2012 in |
The aim of this study was to investigate the antimicrobial, antioxidant and cytotoxic effects of the bark of Terminalia arjuna. The plant part was extracted with methanol to yield the crude extract. The antimicrobial activity test of the methanol extract of the bark of Terminalia arjuna was done using disc diffusion method. Standard antibiotic discs of Kanamycin (30 μg/disc) were used as standard. The crude extract was used at a concentration of 500μg/disc. All the microorganisms were susceptible in various degrees to the extract. The methanol extract was found to be moderately active against Staphylococus aereus, Bacillus megaterium, Bacillus subtilis Salmonella typhi, Escherichia coli and Pseudomonas aeruginosa. The zone of inhibition was found from 12 mm to 19 mm. The crude methanol extract was again studied for investigating free radical scavenging potentiality and was subjected to this study with 2, 2-Diphenyl-1-picrylhydrazyl (DPPH). The methanol extract of the bark of the plant exhibited the potential free radical scavenging activity (antioxidant effect) having IC50 value of 7.05 µg/ml. The cytotoxic activity...
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Posted by admin on Jan 1, 2012 in |
The present study is aimed at evaluating the in vitro antibacterial and antifungal activities of petroleum ether, chloroform, ethyl acetate, acetone, methanol, ethanol and water extracts of medicinal plant, Pyrus pashia were tested against (different gram positive and gram negative) ten bacterial strains and three fungal strains using by disc diffusion method. The different fractions of bark, fruit and leaf of Pyrus pashia, the ethanolic bark extracts of Pyrus pashia showed significant activity 17±1mm, 15±1mm and 14±1mm against Klebsiella pneumonia, Shigella flexneri and Escherichia coli. The medicinal plant fruit contain ash value, (total ash 1.10 ± 0.05%), moisture 60.36±0.25%, crude fat 1.62±0.20% and crude fiber 5.26±0.05%, extractive values were studied fresh part weight. The preliminary phytochemical analysis test showed the presence of carbohydrates (28.38±0.12%) and glycosides, alkaloid, flavonoids, saponins, tannins, unsaturated triterpenoids and sterol,...
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Posted by admin on Dec 1, 2011 in |
Studies have been demonstrating that Vismia guianensis (Aubl.) Choisy, popularly known as seal, a species native to South America has high anticancer and antimicrobial potential. The objective of this study was to evaluate the antimicrobial activity of the ethanolic extract obtained from the leaves of V. guianensis, and trace its chemical profile. The phytochemical screening showed the presence of different phenolic compounds in the extract. The high performance liquid chromatography performed on the sub-fractions A and B from the ethyl acetate fraction traced the chemical composition profile of the ethanol extract, composed by benzophenone, xanthones and anthraquinones. The antimicrobial activity of the extract evaluated by agar diffusion method showed inhibition against Gram-positive bacteria: Streptococcus mitis (ATCC 903), Streptococcus sanguis (ATCC 10557) and Staphylococcus aureus (ATCC 6538) and the fungi: Candida albicans (ATCC 40175), Candida krusei (ATCC 40147) and Candida parapsilosis (ATCC...
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Posted by admin on Dec 1, 2011 in |
The essential oil of the aerial parts of Launaea nudicaulis was isolated using Clevenger’s apparatus and analyzed by GC/MS instrument. Different extracts of the aerial parts of Launaea nudicaulis were tested for their activity against Staphylococcus aureus and Escherichia coli. Seventeen constituents were identified in the essential oil. The major constituents in the essential oil are limonene, Z-citral and E-citral. The three polar extracts (hydro alcoholic, Ethyl acetate and butanol extracts) showed good activity against Gram +ve and Gram-ve bacteria. On the other hand, non-polar extracts (petroleum ether extract and chloroform extract) did not show any antibacterial...
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