Posted by admin on Aug 1, 2011 in |
Since ancient times, plants have got medicinal importance. Ethno medicinal use of plants is very common in rural parts of India. Various constituents of these plants have shown profound therapeutic and prophylactic activities. The present research work is conducted to investigate invitro antimicrobial activity of various extracts of seeds of plant Cleome viscosa Linn. The petroleum ether, chloroform, ethyl acetate, ethanol & water extract of seeds of plants were screened against eight microbial species. Clinical samples of pus from earache patients were also used. The test materials have shown significant antimicrobial activity. The zones of inhibition are found to be between 10 mm to 17 mm. The minimum inhibitory concentration (MIC) values of extracts are also determined against microorganism which ranges from 0.1 to...
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Posted by admin on Jul 1, 2011 in |
Herbal medicines are widely used since time immemorial indicating that herbs are a growing part of modern, high-tech medicine.India has an ancient heritage of traditional herbal medicine. The World Health Organization estimates that about 80% of the populations living in the developing countries rely almost exclusively on traditional medicine for their primary health care needs. The use of herbal drugs for treating various diseases predates human history forms the origin of much of the modern medicine.The medicinal plants are used for various diseases because of their safety and effectiveness. The problem of microbial resistance is growing and the outlook for the use of antimicrobial drugs in the future is still uncertain. Therefore, actions must be taken to control the use of antibiotic, to develop research to better understand the genetic mechanisms of resistance, and to continue studies to develop either synthetic or natural new drugs. Numerous studies have been done on herbals confirming their potential antimicrobial property against microorganisms. One of the strategies towards attaining this objective is the...
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Posted by admin on Jul 1, 2011 in |
The study is aimed towards studying synergistic antimicrobial effect of cow urine and Azadirachta indica against bacterial, fungal and yeast strains. Mother Nature is the best healer. Last few decades have seen tremendous development in pharma sector. Even though these industries have produced a large number of new drugs and new antibiotics and so does the resistance among microbes is growing. Bacterial strains used were Streptomyces aureofaciens (MTCC 325), E.coli (MTCC 448), Streptococcus mutans (MTCC 497) and Pseudomonas aeruginosa (MTCC 7093). Fungal strains used were Candida albicans (MTCC183) and yeasts like Candida paraopsilosis (MTCC 1965), Candida tropicalis (MTCC 184), and Candida glabrata (MTCC 3019). When equilibrated amount of cow urine is used with Azadirachta indica remarkable synergistic effects were observed in the case of C. tropicalis, C. glabrata, P. aeruginosa, S. aureofaciens....
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Posted by admin on Jun 1, 2011 in |
Some N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene) imino] phenyl}-2-(substituted phenoxy) acetamide derivatives (3) were synthesized by reacting N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene) imino] phenyl}-2-chloroacetamide (2) with some substituted phenol in dry acetone in the presence of K2CO3 and catalytic amount of KI. The chemical structures of the compounds were elucidated by IR, 1H-NMR and elemental analysis. Their antibacterial activity against gram positive bacterial strains (S. aureus and B. subtilis) and gram negative bacterial strains (E. coli and P. aeruginosa) were investigated by disc diffusion method. The antifungal activity of these compounds was also tested against A. niger and A. flavipes. The results showed that some of the compounds have strong antimicrobial...
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Posted by admin on Jun 1, 2011 in |
A series of 1, 3, 4-thiadiazole derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and mass spectrum analysis. All the compounds were evaluated for antibacterial and antifungal activities. Most of the compounds have shown significant antibacterial and antifungal activity when compared with the standard...
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